United States - English - NLM (National Library of Medicine)

mylan institutional inc. - loperamide hydrochloride (unii: 77ti35393c) (loperamide - unii:6x9oc3h4ii) - loperamide hydrochloride 2 mg - loperamide hydrochloride capsules are indicated for the control and symptomatic   relief of acute nonspecific diarrhea in patients 2 years of age and older and of chronic diarrhea in adults associated with inflammatory   bowel disease. loperamide hydrochloride capsules are also indicated for reducing the volume of discharge from   ileostomies. loperamide hydrochloride capsules are contraindicated in: - pediatric patients less than 2 years of age due to the risks of respiratory depression and serious cardiac adverse reactions (see warnings). - patients with a known hypersensitivity to loperamide hydrochloride or to any of the excipients. - patients with abdominal pain in the absence of diarrhea. - patients with acute dysentery, which is characterized by blood in stools and high fever. - patients with acute ulcerative colitis. - patients with bacterial

United States - English - NLM (National Library of Medicine)

cardinal health 107, llc - loperamide hydrochloride (unii: 77ti35393c) (loperamide - unii:6x9oc3h4ii) - loperamide hydrochloride 2 mg - loperamide hydrochloride capsules are indicated for the control and symptomatic  relief of acute nonspecific diarrhea in patients 2 years of age and older and of chronic diarrhea in adults associated with inflammatory  bowel disease. loperamide hydrochloride capsules are also indicated for reducing the volume of discharge from  ileostomies. loperamide hydrochloride capsules are contraindicated in: loperamide is not a controlled substance. loperamide is a mu-opioid agonist. a human abuse potential study of loperamide hydrochloride at single doses up to 60 mg (3.75 times the recommended maximum adult dosage of 16 mg per day) was compared, in a double-blind cross-over design using nine subjects who had been active opiate users, to a threshold dose of codeine sulfate at 120 mg (96 mg base) or placebo. this resulted in one subject (11%) feeling a drug on placebo and identifying it as "dope" (heroin) and liking it slightly. codeine was felt by 56% of subjects and identified as "dope" by 44%. loperamide was felt by 44% of subjects and identified as "dope" by 11% and possibly dope mixed with some other kind of drug by another 22%. loperamide abuse and misuse have been reported, especially at doses of 60 mg or greater. loperamide can have greater cns opioid effects at higher doses or with coadministration of drugs that increase systemic exposure and/or increase cns penetration of loperamide (through inhibition of the cyp450 enzyme system or inhibition of p-glycoprotein). loperamide is primarily being misused for relief from opioid withdrawal, and abused by a few users who obtain some (reportedly mild-moderate) level of euphoria. in animals, parenteral administration of loperamide hydrochloride can cause physical dependence, cross-tolerance to opioids, and all the other pharmacologic effects typical of mu-opioid agonists. studies in morphine-dependent monkeys demonstrated that loperamide hydrochloride at doses above those recommended for humans prevented signs of morphine withdrawal.

United States - English - NLM (National Library of Medicine)

contract pharmacy services-pa - loperamide hydrochloride (unii: 77ti35393c) (loperamide - unii:6x9oc3h4ii) - loperamide hydrochloride 2 mg - loperamide hydrochloride capsules are indicated for the control and symptomatic   relief of acute nonspecific diarrhea in patients 2 years of age and older and of chronic diarrhea in adults associated with inflammatory   bowel disease. loperamide hydrochloride capsules are also indicated for reducing the volume of discharge from   ileostomies. loperamide hydrochloride capsules are contraindicated in: - pediatric patients less than 2 years of age due to the risks of respiratory depression and serious cardiac adverse reactions (see warnings). - patients with a known hypersensitivity to loperamide hydrochloride or to any of the excipients. - patients with abdominal pain in the absence of diarrhea. - patients with acute dysentery, which is characterized by blood in stools and high fever. - patients with acute ulcerative colitis. - patients with bacterial enterocolitis caused by invasive organisms including salmonella , shigella ,

United States - English - NLM (National Library of Medicine)

remedyrepack inc. - loperamide hydrochloride (unii: 77ti35393c) (loperamide - unii:6x9oc3h4ii) - loperamide hydrochloride 2 mg - loperamide hydrochloride is indicated for the control and symptomatic relief of acute nonspecific diarrhea in patients 2 years of age and older and of chronic diarrhea in adults associated with inflammatory bowel disease. loperamide hydrochloride capsules are also indicated for reducing the volume of discharge from ileostomies. loperamide hydrochloride capsules are contraindicated in: - pediatric patients less than 2 years of age due to the risks of respiratory depression and serious cardiac adverse reactions (see warnings ). - patients with a known hypersensitivity to loperamide hydrochloride or to any of the excipients. - patients with abdominal pain in the absence of diarrhea. - patients with acute dysentery, which is characterized by blood in stools and high fever. - patients with acute ulcerative colitis. - patients with bacterial enterocolitis caused by invasive organisms including salmonella , shigella , and campylobacter . - patients with pseudomembranous colitis (e.g., clostridium difficile ) associated with the use of broad-spectrum antibiotics. loperamide is not a controlled substance. loperamide is a mu-opioid agonist. a human abuse potential study of loperamide hydrochloride at single doses up to 60 mg (3.75 times the recommended maximum adult dosage of 16 mg per day) was compared, in a double-blind cross-over design using nine subjects who had been active opiate users, to a threshold dose of codeine sulfate at 120 mg (96 mg base) or placebo. this resulted in one subject (11%) feeling a drug on placebo and identifying it as "dope" (heroin) and liking it slightly. codeine was felt by 56% of subjects and identified as "dope" by 44%. loperamide was felt by 44% of subjects and identified as "dope" by 11% and possibly dope mixed with some other kind of drug by another 22%. loperamide abuse and misuse have been reported, especially at doses of 60 mg or greater. loperamide can have greater cns opioid effects at higher doses or with coadministration of drugs that increase systemic exposure and/or increase cns penetration of loperamide (through inhibition of the cyp450 enzyme system or inhibition of p-glycoprotein). loperamide is primarily being misused for relief from opioid withdrawal, and abused by a few users who obtain some (reportedly mild-moderate) level of euphoria. in animals, parenteral administration of loperamide hydrochloride can cause physical dependence, cross-tolerance to opioids, and all the other pharmacologic effects typical of mu-opioid agonists. studies in morphine-dependent monkeys demonstrated that loperamide hydrochloride at doses above those recommended for humans prevented signs of morphine withdrawal.

Belgium - English - AFMPS (Agence Fédérale des Médicaments et des Produits de Santé)

aurobindo sa-nv - loperamide hydrochloride 2 mg - capsule, hard - 2 mg - loperamide hydrochloride 2 mg - loperamide

Belgium - English - AFMPS (Agence Fédérale des Médicaments et des Produits de Santé)

eg sa-nv - loperamide hydrochloride 2 mg - capsule, hard - 2 mg - loperamide hydrochloride 2 mg - loperamide

Belgium - English - AFMPS (Agence Fédérale des Médicaments et des Produits de Santé)

teva pharma belgium sa-nv - loperamide hydrochloride 2 mg - capsule, hard - 2 mg - loperamide hydrochloride 2 mg - loperamide

Belgium - English - AFMPS (Agence Fédérale des Médicaments et des Produits de Santé)

aurobindo sa-nv - loperamide hydrochloride 2 mg - orodispersible tablet - 2 mg - loperamide hydrochloride 2 mg - loperamide

Ireland - English - HPRA (Health Products Regulatory Authority)

tenshi kaizen b.v. - loperamide hydrochloride - oral lyophilisate - loperamide

United States - English - NLM (National Library of Medicine)

bryant ranch prepack - loperamide hydrochloride (unii: 77ti35393c) (loperamide - unii:6x9oc3h4ii) - loperamide hydrochloride 2 mg - loperamide hydrochloride is indicated for the control and symptomatic relief of acute nonspecific diarrhea in patients 2 years of age and older and of chronic diarrhea in adults associated with inflammatory bowel disease. loperamide hydrochloride capsules are also indicated for reducing the volume of discharge from ileostomies. loperamide hydrochloride capsules are contraindicated in: - pediatric patients less than 2 years of age due to the risks of respiratory depression and serious cardiac adverse reactions (see warnings ). - patients with a known hypersensitivity to loperamide hydrochloride or to any of the excipients. - patients with abdominal pain in the absence of diarrhea. - patients with acute dysentery, which is characterized by blood in stools and high fever. - patients with acute ulcerative colitis. - patients with bacterial enterocolitis caused by invasive organisms including salmonella , shigella , and campylobacter . - patients with pseudomembranous colitis (e.g., clostridium difficile ) associa